We developed this web-based server to process 4C-Seq data generated from Illumina
high-throughput sequencers, such as HiSeq 2000. In the last decade, long-range chromatin-chromatin interaction in the nucleus has
been gradually recognized as an epigenetic regulator. In particular, a high-throughput sequencing approach (4C-Seq) based on circular
chromosome conformation capture (4C) has been developed to explore genome-wide interactions of a particular locus. Unlike array-based
genomic data, processing of next-generation sequencing (NGS) data is a big challenge for a bench scientist.
This w4CSeq web server aimed to provide a simple and easy to use interface for the
users to process 4C-Seq raw data generated by an Illumina sequencer, therefore even the users without bioinformatics background can
extract biological insight from millions lines of AGCT reads.